منابع مشابه
Glycated Haemoglobin: A Predictor of Vascular Risk?
Glycated haemoglobin (HbA1c), a marker of average glycaemia during the previous six to eight weeks, is a predictor of microvascular complications in diabetic individuals. However, the role of HbA1c as a predictor of macrovascular complications (e.g. myocardial infarction or stroke) in these patients is not clearly defined. In contrast, new evidence suggests that HbA1c can predict the risk of ca...
متن کاملd-Ribose as a Contributor to Glycated Haemoglobin
Glycated haemoglobin (HbA1c) is the most important marker of hyperglycaemia in diabetes mellitus. We show that d-ribose reacts with haemoglobin, thus yielding HbA1c. Using mass spectrometry, we detected glycation of haemoglobin with d-ribose produces 10 carboxylmethyllysines (CMLs). The first-order rate constant of fructosamine formation for d-ribose was approximately 60 times higher than that ...
متن کاملArtifactually low glycated haemoglobin in a patient with severe hypertriglyceridaemia.
This report describes a case of artifactually low glycated haemoglobin (Hb) in a patient with type II diabetes and severe hypertriglyceridaemia. The effect of hypertriglyceridaemia on glycated Hb determination using the Abbott Vision method was investigated in a series of patients with diabetes. The interference of triglycerides in glycated Hb assays was also investigated by two other methods, ...
متن کاملAberrantly high glycated haemoglobin measurement due to the haemoglobin variant Hb Santa Juana.
Various laboratory and patient-related factors can result in falsely high or low glycated haemoglobin (HbA1c) measurements, and haemoglobin (Hb) variants that interfere with laboratory readings is an important cause of this. We report a case of a rare Hb variant, Hb Santa Juana, manifesting as a falsely high HbA1c in a 62-year-old patient with type 2 diabetes mellitus. The patient presented wit...
متن کاملCorrelation between glycated haemoglobin levels and random blood glucose.
BACKGROUND Glycated haemoglobin or glycosylated haemoglobin (HbA1c) is a form of haemoglobin that is measured primarily to identify the average plasma glucose concentration over prolonged periods of time. Levels of HbA1c represent the average blood glucose levels of diabetic patients over the previous 120 days. The objective of this study was to see the correlation between HbA1c levels and rand...
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ژورنال
عنوان ژورنال: BMJ
سال: 1992
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.305.6860.1020-b